beta -Arrestin 1(Phospho-Ser412) Rabbit Polyclonal Antibody

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Home > Product > Antibody > beta -Arrestin 1(Phospho-Ser412) Rabbit Polyclonal Antibody

beta -Arrestin 1(Phospho-Ser412) Rabbit Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

Product overview

Full product name

beta -Arrestin 1

Code

BT-AP05811

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized phosho peptide around human β-Arrestin 1 (Ser412)

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones| neurotransmitters| or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system| it is expressed at high levels in peripheral blood leukocytes| and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.

Uniprot accession

Human:;Mouse:;Rat:;

Gene ID

Human: 408; Mouse: 109689; Rat: 25387

Synonyms

β-Arrestin 1 ;Ser412; Beta-arrestin-1; Arrestin beta-1

Research area

Signal transduction; Neuroscience

Target protein

ARRB1

Recommended dilution

Application	Dilution
WB	1: 1000 - 1: 2000
ELISA	1: 20000

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100ul

$275.00
50ul

$180.00
20ul

$108.00

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Lead time: Within one week

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