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Home > Product > Antibody > AMPK alpha 1 Polyclonal Antibody

AMPK alpha 1 Polyclonal Antibody

AMPK alpha 1 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, IF

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, IF

Product overview

Full product name

5'-AMP-activated protein kinase catalytic subunit alpha-1

Code

BT-AP14207

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Recombinant Protein of AMPKα1

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage

-20°C for 1 year

Background

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Uniprot accession

Gene ID

Human: 5562

Synonyms

5'-AMP-activated protein kinase catalytic subunit alpha-1; PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1

Research area

Cancer; Cardiovascular; Metabolism; Signal transduction; Neuroscience

Target protein

PRKAA1

Recommended dilution

Application Dilution
WB 1: 500 - 1000
IHC 1: 200 - 500

Images

Immunohistochemical analysis of paraffin-embedded Mouse Skeletal Muslce Tissue using AMPKα1 Polyclonal Antibody.
Western blot analysis of 1) Hela, 2) 3T3, 3) PC12 using AMPKα1 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Protocols

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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