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Home > Product > Antibody > ATM Rabbit Polyclonal Antibody

ATM Rabbit Polyclonal Antibody

ATM Rabbit Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat, Mouse

Applications: IHC-p, IF

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: IHC-p, IF

Product overview

Full product name

ATM

Code

BT-AP06560

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Recombinant Protein of ATM of ATM

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.

Uniprot accession

Gene ID

Human: 472

Synonyms

ATM; ATM

Research area

Epigenetics and nuclear signaling; Cancer

Target protein

ATM

Recommended dilution

Application Dilution
IHC 1: 100 - 1: 200

Images

Immunohistochemical analysis of paraffin-embedded Human Colon Carcinoma Tissue using ATM Rabbit pAb diluted at 1:500.
Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using ATM Rabbit pAb diluted at 1:500.
Immunohistochemical analysis of paraffin-embedded Human Prostate Carcinoma Tissue using ATM Rabbit pAb diluted at 1:500.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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