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Home > Product > Antibody > Bmi-1 Rabbit Polyclonal Antibody(F270)

Bmi-1 Rabbit Polyclonal Antibody(F270)

Bmi-1 Rabbit Polyclonal Antibody(F270)

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: WB

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: WB

Product overview

Full product name

Bmi-1

Code

BT-AP14458

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Recombinant Protein derived from human Bmi-1

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene.

Uniprot accession

Gene ID

Human: 100532731

Synonyms

Bmi-1; Polycomb complex protein BMI-1; Polycomb group RING finger protein 4; RING finger protein 51

Research area

Cancer; Cell biology; Epigenetics and nuclear signaling; Stem cells

Target protein

BMI1

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000

Protocols

Customer reviews and Q&As

No reviews
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Product size

Price

  • 100ul

    $275.00

  • 50ul

    $180.00

  • 20ul

    $108.00

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Lead time: Within one week

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