Full product name
Voltage-dependent R-type calcium channel subunit alpha-1E
Code
BT-AP14592
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 370-450
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Uniprot accession
Gene ID
Human: 777
Synonyms
Voltage-dependent R-type calcium channel subunit alpha-1E ;Brain calcium channel II;BII;Calcium channel, L type, alpha-1 polypeptide, isoform 6;Voltage-gated calcium channel subunit alpha Cav2.3
Research area
Cancer; Metabolism; Neuroscience; Signal transduction
Target protein
CACNA1E