Cdc25A(Phospho Ser178) Polyclonal Antibody

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Blood coagulation
Metabolism
Cancer
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Cell biology
Signal transduction
Developmental biology
Stem cells
Epigenetics and nuclear signaling
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Home > Product > Antibody > Cdc25A(Phospho Ser178) Polyclonal Antibody

Cdc25A(Phospho Ser178) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

M-phase inducer phosphatase 1

Code

BT-AP07487

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human CDC25A around the phosphorylation site of Ser178. AA range:144-193

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

59087

Gene ID

Human: 993; Rat: 171102

Synonyms

M-phase inducer phosphatase 1; CDC25A; M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A

Research area

Cancer; Cell biology; Epigenetics and nuclear signaling

Target protein

CDC25A

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC-p	1: 100 - 1: 300
ELISA	1: 10000

Images

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using CDC25A (Phospho-Ser178) Antibody. The picture on the right is blocked with the phospho peptide.

Western blot analysis of lysates from A549 cells treated with UV 15', using CDC25A (Phospho-Ser178) Antibody. The lane on the right is blocked with the phospho peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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