Full product name
Cyclin-dependent kinase inhibitor 3
Code
BT-AP07568
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human CDKN3 Polyclonal
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Uniprot accession
Gene ID
Human: 1033; Mouse: 72391
Synonyms
Cyclin-dependent kinase inhibitor 3 ;EC 3.1.3.16;EC 3.1.3.48;CDK2-associated dual-specificity phosphatase;Cyclin-dependent kinase interactor 1;Cyclin-dependent kinase-interacting protein 2;K; Cyclin-dependent kinase inhibitor 3; EC 3.1.3.16; EC 3.1.3.48; CDK2-associated dual-specificity phosphatase; Cyclin-dependent kinase interactor 1; Cyclin-dependent kinase-interacting protein 2; Kinase-associated phosphatase
Research area
Cancer; Cell biology; Signal transduction
Target protein
CDKN3
