CXCR4 Polyclonal Antibody

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Home > Product > Antibody > CXCR4 Polyclonal Antibody

CXCR4 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat, Mouse

Applications: WB, IHC-p, IF

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB, IHC-p, IF

Product overview

Full product name

C-X-C chemokine receptor type 4

Code

BT-AP15126

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Synthetic Peptide of CXCR4

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Uniprot accession

Human:;Mouse:;Rat:;

Gene ID

Human: 7852

Synonyms

C-X-C chemokine receptor type 4 ;CXC-R4;CXCR-4;FB22;Fusin;HM89;LCR1;Leukocyte-derived seven transmembrane domain receptor;LESTR;NPYRL;Stromal cell-derived factor 1 receptor;SDF-1 r; CXCR4; C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; FB22; Fusin; HM89; LCR1; Leukocyte-derived seven transmembrane domain receptor; LESTR; NPYRL; Stromal cell-derived factor 1 receptor; SDF-1 receptor; CD antigen CD184

Research area

Cancer; Immunology; Metabolism; Microbiology; Neuroscience; Stem cells

Target protein

CXCR4

Recommended dilution

Application	Dilution
WB	1: 1000 - 1: 2000
IHC	1: 100 - 1: 200

Images

Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma using CXCR4Rabbit pAb diluted at 1:200.

Immunohistochemical analysis of paraffin-embedded Human Tonsil Tissue using CXCR4Rabbit pAb diluted at 1:200.

Western blot analysis of 1) Rat Brain Tissue, 2)Hela, with CXCR4 Rabbit pAb diluted at 1:2,000.

Western blot analysis of lysates from 1) Rat Brain Tissue, 2)Hela, 3) HEK293 cells, (Green) primary antibody was diluted at 1:1000, 4°C overnight, secondary antibody was diluted at 1:10000, 37°C 1hour. (Red) GAPDH Monoclonal Antibody(2B8) was diluted at 1:5000 as loading control, 4°C overnight,secondary antibody was diluted at 1:10000, 37°C 1hour.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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