Cyclin E2(Phospho Thr392) Polyclonal Antibody

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Blood coagulation
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Epigenetics and nuclear signaling
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Home > Product > Antibody > Cyclin E2(Phospho Thr392) Polyclonal Antibody

Cyclin E2(Phospho Thr392) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: IF, ICC, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: IF, ICC, ELISA

Product overview

Full product name

G1/S-specific cyclin-E2

Code

BT-AP15146

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human Cyclin E2 around the phosphorylation site of Thr392. AA range:355-404

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells.

Uniprot accession

Human:;Mouse:;

Molecular weight

46757

Gene ID

Human: 9134; Mouse: 12448

Synonyms

G1/S-specific cyclin-E2; CCNE2; G1/S-specific cyclin-E2

Research area

Cancer; Cell biology; Epigenetics and nuclear signaling

Target protein

CCNE2

Recommended dilution

Application	Dilution
IF	1: 200 - 1: 1000
ICC	1: 200 - 1: 1000
ELISA	1: 10000

Images

Immunofluorescence analysis of NIH/3T3 cells, using Cyclin E2 (Phospho-Thr392) Antibody. The picture on the right is blocked with the phospho peptide.

Western blot analysis of Cyclin E2 (Phospho-Thr392) Antibody. The lane on the right is blocked with the Cyclin E2 (Phospho-Thr392) peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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