Full product name
Probable ATP-dependent RNA helicase DHX58
Code
BT-AP15235
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 451-500
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
Negative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58-mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA.,Belongs to the helicase family.,Contains 1 helicase ATP-binding domain.,Contains 1 helicase C-terminal domain.,subunit:Interacts with DDX58 and probably blocks its homomultimerization.,
Uniprot accession
Gene ID
Human: 79132
Synonyms
Probable ATP-dependent RNA helicase DHX58 ;EC 3.6.4.13;Probable ATP-dependent helicase LGP2;Protein D11Lgp2 homolog;RIG-I-like receptor 3;RLR-3;RIG-I-like receptor LGP2;RLR
Research area
Epigenetics and nuclear signaling; Immunology
Target protein
DHX58
