Full product name
Dedicator of cytokinesis protein 11
Code
BT-AP15266
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
The DHR-2 domain is necessary for the GEF activity.,Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.,miscellaneous:'Zizim' means 'spike' in Hebrew.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the DOCK family.,Contains 1 DHR-1 (CZH-1) domain.,Contains 1 DHR-2 (CZH-2) domain.,Contains 1 PH domain.,subunit:Interacts with CDC42.,
Uniprot accession
Gene ID
Human: 139818
Synonyms
Dedicator of cytokinesis protein 11 ;Activated Cdc42-associated guanine nucleotide exchange factor;ACG;Zizimin-2
Research area
Cell biology; Epigenetics and nuclear signaling
Target protein
DOCK11
