DSC3 Polyclonal Antibody

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Home > Product > Antibody > DSC3 Polyclonal Antibody

DSC3 Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat, Mouse

Applications: WB, ELISA

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB, ELISA

Product overview

Full product name

Desmocollin-3

Code

BT-AP08628

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from part region of human protein

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants.

Uniprot accession

Human:;Mouse:;

Gene ID

Human: 1825

Synonyms

Desmocollin-3 ;Cadherin family member 3;Desmocollin-4;HT-CP

Research area

Signal transduction

Target protein

DSC3

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 5000 - 1: 20000

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100ul

$275.00
50ul

$180.00
20ul

$108.00

Add to Cart

Lead time: Within one week

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