EpoR(Phospho Tyr368) Polyclonal Antibody

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Blood coagulation
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Cell biology
Signal transduction
Developmental biology
Stem cells
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Home > Product > Antibody > EpoR(Phospho Tyr368) Polyclonal Antibody

EpoR(Phospho Tyr368) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IF, ICC, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IF, ICC, ELISA

Product overview

Full product name

Erythropoietin receptor

Code

BT-AP08926

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human Epo-R around the phosphorylation site of Tyr368. AA range:341-390

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

55065

Gene ID

Human: 2057; Mouse: 13857

Synonyms

Erythropoietin receptor; EPOR; Erythropoietin receptor; EPO-R

Research area

Cardiovascular; Immunology; Signal transduction; Stem cells

Target protein

EPOR

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IF	1: 200 - 1: 1000
ICC	1: 200 - 1: 1000
ELISA	1: 10000

Images

Immunofluorescence analysis of HepG2 cells, using Epo-R (Phospho-Tyr368) Antibody. The picture on the right is blocked with the phospho peptide.

Western Blot analysis of K562 cells using Phospho-EpoR (Y368) Polyclonal Antibody

Western blot analysis of lysates from K562 cells, using Epo-R (Phospho-Tyr368) Antibody. The lane on the right is blocked with the phospho peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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