Full product name
Heart- and neural crest derivatives-expressed protein 2
Code
BT-AP09812
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.
Uniprot accession
Gene ID
Human: 9464
Synonyms
Heart- and neural crest derivatives-expressed protein 2 ;Class A basic helix-loop-helix protein 26;bHLHa26;Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein
Research area
Cardiovascular; Epigenetics and nuclear signaling; Neuroscience
Target protein
HAND2