HDAC8(Phospho Ser39) Polyclonal Antibody

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Blood coagulation
Metabolism
Cancer
Microbiology
Cardiovascular
Neuroscience
Cell biology
Signal transduction
Developmental biology
Stem cells
Epigenetics and nuclear signaling
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Immunology

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Home > Product > Antibody > HDAC8(Phospho Ser39) Polyclonal Antibody

HDAC8(Phospho Ser39) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Histone deacetylase 8

Code

BT-AP09852

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human HDAC8 around the phosphorylation site of Ser39. AA range:5-54

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

41758

Gene ID

Human: 55869; Mouse: 70315; Rat: 1.00912e+008

Synonyms

Histone deacetylase 8; HDAC8; HDACL1; CDA07; Histone deacetylase 8; HD8

Research area

Cardiovascular; Epigenetics and nuclear signaling; Stem cells

Target protein

HDAC8

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC-p	1: 100 - 1: 300
ELISA	1: 20000

Images

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using HDAC8 (Phospho-Ser39) Antibody. The picture on the right is blocked with the phospho peptide.

Western Blot analysis of various cells using Phospho-HDAC8 (S39) Polyclonal Antibody diluted at 1:500

Western Blot analysis of VEC cells using Phospho-HDAC8 (S39) Polyclonal Antibody diluted at 1:500

Western blot analysis of lysates from NIH/3T3 cells, using HDAC8 (Phospho-Ser39) Antibody. The lane on the right is blocked with the phospho peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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