Full product name
Histone H2A.x
Code
BT-AP09931
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthetic Peptide of Histone H2A.X (Phospho Tyr142)
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Storage
-20°C for 1 year
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Uniprot accession
Gene ID
Human: 3014; Mouse: 15270
Synonyms
Histone H2A.x; H2AFX; H2AX; Histone H2A.x; H2a/x
Research area
Epigenetics and nuclear signaling
Target protein
H2AFX
