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Home > Product > Antibody > HUS1 Polyclonal Antibody

HUS1 Polyclonal Antibody

HUS1 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat, Mouse

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB, ELISA

Product overview

Full product name

Checkpoint protein HUS1

Code

BT-AP10230

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from human protein . at AA range: 160-240

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants.

Uniprot accession

Gene ID

Human: 3364

Synonyms

Checkpoint protein HUS1 ;hHUS1

Research area

Epigenetics and nuclear signaling

Target protein

HUS1

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
ELISA 1: 5000 - 1: 20000

Images

Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°C overnight

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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