Full product name
Interleukin-27 receptor subunit alpha
Code
BT-AP10259
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.
Uniprot accession
Gene ID
Human: 9466
Synonyms
Interleukin-27 receptor subunit alpha ;IL-27 receptor subunit alpha;IL-27R subunit alpha;IL-27R-alpha;IL-27RA;Cytokine receptor-like 1;Type I T-cell cytokine receptor;TCCR;WSX-1;ZcytoR
Research area
Epigenetics and nuclear signaling; Immunology; Signal transduction
Target protein
IL27RA
