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Home > Product > Antibody > Insulin R(Phospho Tyr1355) Polyclonal Antibody

Insulin R(Phospho Tyr1355) Polyclonal Antibody

Insulin R(Phospho Tyr1355) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat, Mouse

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Insulin receptor

Code

BT-AP10408

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human IR around the phosphorylation site of Tyr1355. AA range:1326-1375

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.

Uniprot accession

Molecular weight

156307

Gene ID

Human: 3643

Synonyms

Insulin receptor; INSR; Insulin receptor; IR; CD antigen CD220

Research area

Cardiovascular; Metabolism; Neuroscience ; Signal transduction; Cancer

Target protein

INSR

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
IHC-p 1: 100 - 1: 300
ELISA 1: 10000

Images

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using IR (Phospho-Tyr1355) Antibody. The picture on the right is blocked with the phospho peptide.
Western Blot analysis of 293 cells using Phospho-Insulin R (Y1355) Polyclonal Antibody
Western blot analysis of lysates from 293 cells treated with Heat shock, using IR (Phospho-Tyr1355) Antibody. The lane on the right is blocked with the phospho peptide.

Protocols

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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