Integrin beta 4(Phospho Tyr1510) Polyclonal Antibody

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Home > Product > Antibody > Integrin beta 4(Phospho Tyr1510) Polyclonal Antibody

Integrin beta 4(Phospho Tyr1510) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Integrin beta-4

Code

BT-AP10441

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human ITGB4 around the phosphorylation site of Tyr1510. AA range:1481-1530

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

202151

Gene ID

Human: 3691; Rat: 25724

Synonyms

Integrin beta-4; ITGB4; Integrin beta-4; GP150; CD antigen CD104

Research area

Signal transduction

Target protein

ITGB4

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC-p	1: 100 - 1: 300
ELISA	1: 10000

Images

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using ITGB4 (Phospho-Tyr1510) Antibody. The picture on the right is blocked with the phospho peptide.

Western Blot analysis of AD293 using Phospho-Integrin β4 (Y1510) Polyclonal Antibody. Antibody was diluted at 1:500

Western blot analysis of lysates from HepG2 cells treated with Na2VO3 0.3nM 40', using ITGB4 (Phospho-Tyr1510) Antibody. The lane on the right is blocked with the phospho peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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