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Home > Product > Antibody > IκB-alpha Polyclonal Antibody

IκB-alpha Polyclonal Antibody

IκB-alpha Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat

Applications: WB, IHC-p, IF

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat

Applications: WB, IHC-p, IF

Product overview

Full product name

NF-kappa-B inhibitor alpha

Code

BT-AP10545

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Recombinant Protein of IκB-α

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage

-20°C for 1 year

Background

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Uniprot accession

Gene ID

Human: 4792

Synonyms

NF-kappa-B inhibitor alpha; NFKBIA; IKBA; MAD3; NFKBI; NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3

Research area

Cancer; Epigenetics and nuclear signaling; Immunology; Signal transduction

Target protein

NFKBIA

Recommended dilution

Application Dilution
WB 1: 2000 - 1: 5000
IHC 1: 200 - 1: 500

Images

Immunohistochemical analysis of paraffin-embedded Human KidneyTissue using IκB-α Polyclonal Antibody.
Western blot analysis of 1) Hela, 2) PC12 using IκB-α Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Protocols

Customer reviews and Q&As

No reviews
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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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