Full product name
Histone acetyltransferase KAT6A
Code
BT-AP10618
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 160-240
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with autosomal dominant mental retardation-32. Alternative splicing results in multiple transcript variants.
Uniprot accession
Gene ID
Human: 7994
Synonyms
Histone acetyltransferase KAT6A ;EC 2.3.1.48;MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3;MYST-3;Monocytic leukemia zinc finger protein;Runt-related transcription factor-binding protein 2;Zinc f
Research area
Epigenetics and nuclear signaling
Target protein
KAT6A
