Full product name
Lysine-specific demethylase 4D
Code
BT-AP10663
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 400-480
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
It is uncertain whether Met-1 or Met-4 is the initiator.,cofactor:Binds 1 Fe(2+) ion per subunit.,Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.,Belongs to the JHDM3 histone demethylase family.,Contains 1 JmjC domain.,Contains 1 JmjN domain.,
Uniprot accession
Gene ID
Human: 55693
Synonyms
Lysine-specific demethylase 4D ;EC 1.14.11.-;JmjC domain-containing histone demethylation protein 3D;Jumonji domain-containing protein 2D
Research area
Epigenetics and nuclear signaling
Target protein
KDM4D
