LAT(Phospho Tyr200) Polyclonal Antibody

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Home > Product > Antibody > LAT(Phospho Tyr200) Polyclonal Antibody

LAT(Phospho Tyr200) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

Product overview

Full product name

Linker for activation of T-cells family member 1

Code

BT-AP10842

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human LAT around the phosphorylation site of Tyr171. AA range:171-220

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

27930

Gene ID

Human: 27040; Mouse: 16797; Rat: 81511

Synonyms

Linker for activation of T-cells family member 1; LAT; Linker for activation of T-cells family member 1; 36 kDa phospho-tyrosine adapter protein; pp36; p36-38

Research area

Immunology; Signal transduction

Target protein

LAT

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 10000

Images

Western blot analysis of lysates from Jurkat cells treated with UV 15', using LAT (Phospho-Tyr171) Antibody. The lane on the right is blocked with the phospho peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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