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Home > Product > Antibody > MEK-5 Polyclonal Antibody

MEK-5 Polyclonal Antibody

MEK-5 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, IF

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, IF

Product overview

Full product name

Dual specificity mitogen-activated protein kinase kinase 5

Code

BT-AP11265

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Recombinant Protein of MEK-5

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage

-20°C for 1 year

Background

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.

Uniprot accession

Gene ID

Human: 5067

Synonyms

Dual specificity mitogen-activated protein kinase kinase 5; MAP2K5; MEK5; MKK5; PRKMK5; Dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPKK 5; MAPK/ERK kinase 5; MEK 5

Research area

Cancer; Cardiovascular; Signal transduction

Target protein

MAP2K5

Recommended dilution

Application Dilution
WB 1: 1000 - 1: 2000
IHC 1: 200 - 500

Images

Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma using MEK-5 Polyclonal Antibody.
Western blot analysis of 1) Hela, 2) 3T3, 3) PC12 using MEK-5 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Protocols

Customer reviews and Q&As

No reviews
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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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