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Home > Product > Antibody > Met Rabbit Polyclonal Antibody

Met Rabbit Polyclonal Antibody

Met Rabbit Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat, Mouse

Applications: IHC-p, IF

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: IHC-p, IF

Product overview

Full product name

MET

Code

BT-AP11300

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Recombinant Protein of Met of MET

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers.

Uniprot accession

Gene ID

Human: 4233

Synonyms

MET; MET

Research area

Cancer; Epigenetics and nuclear signaling; Signal transduction

Target protein

MET

Recommended dilution

Application Dilution
IHC 1: 100 - 1: 200

Images

Immunohistochemical analysis of paraffin-embedded Human Lung Carcinoma Tissue using Met Rabbit pAb diluted at 1:500.
Immunohistochemical analysis of paraffin-embedded Human Stomach Carcinoma Tissue using Met Rabbit pAb diluted at 1:500.
Immunohistochemical analysis of paraffin-embedded Human Liver Carcinoma Tissue using Met Rabbit pAb diluted at 1:500.

Protocols

Customer reviews and Q&As

No reviews
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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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