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Home > Product > Antibody > MLK1/2(Phospho Thr312/266) Polyclonal Antibody

MLK1/2(Phospho Thr312/266) Polyclonal Antibody

MLK1/2(Phospho Thr312/266) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: IHC-p, IF, ELISA

Product overview

Full product name

Mitogen-activated protein kinase kinase kinase 9/10

Code

BT-AP11373

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human MLK1/2 around the phosphorylation site of Thr312/266. AA range:281-330

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation.,Activates the JUN N-terminal pathway.,PTM:Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation. Thr-312 is likely to be the main autophosphorylation site.,Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,Contains 1 protein kinase domain.,Contains 1 SH3 domain.,subunit:Homodimer.,tissue specificity:Expressed in epithelial tumor cell lines of colonic, breast and esophageal origin.,

Uniprot accession

Molecular weight

121895;103694

Gene ID

Human: 4293/4294; Mouse: 338372

Synonyms

Mitogen-activated protein kinase kinase kinase 9/10; MAP3K9; MLK1; PRKE1; Mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; MAP3K10; MLK2; MST; Mitogen-activated protein kinase kinase kinase 10; Mixed lineage kinase 2; Protein kinase MST

Research area

Cell biology; Signal transduction

Target protein

MAP3K9

Recommended dilution

Application Dilution
IHC-p 1: 100 - 1: 300
ELISA 1: 5000

Images

Immunohistochemistry analysis of paraffin-embedded human brain, using MLK1/2 (Phospho-Thr312/266) Antibody. The picture on the right is blocked with the phospho peptide.

Protocols

Customer reviews and Q&As

No reviews
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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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