Full product name
Histone-lysine N-methyltransferase MLL4
Code
BT-AP11382
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 1060-1140
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known.
Uniprot accession
Gene ID
Human: 9757
Synonyms
Histone-lysine N-methyltransferase MLL4 ;EC 2.1.1.43;Lysine N-methyltransferase 2B;KMT2B;Myeloid/lymphoid or mixed-lineage leukemia protein 4;Trithorax homolog 2;WW domain-binding protein 7
Research area
Epigenetics and nuclear signaling
Target protein
WBP7
