Full product name
Putative neuropeptide Y receptor type 6
Code
BT-AP12000
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 190-270
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
Could be the product of a pseudogene. According to PubMed:97066888, PubMed:97066971 and PubMed:9013614, the human NPY6R gene is an expressed pseudogene containing a premature stop codon and encoding a non-functional truncated protein missing the last transmembrane domain. A single base pair deletion relative to the mouse ortholog, results in a truncated protein lacking the seventh transmembrane domain.,When expressed, is unable to bind pancreatic polypeptide (PP), neuropeptide Y (NPY), or peptide YY (PYY), suggesting that either it is functionally inactive or that it may have acquired a pancreatic polypeptide-independent function.,Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in heart, skeletal muscle, gastrointestinal tissues, spleen, brain and adrenal glands.,
Uniprot accession
Synonyms
Putative neuropeptide Y receptor type 6 ;NPY6-R;NPY Y1-like receptor;Putative pancreatic polypeptide receptor 2;PP2
Research area
Neuroscience; Epigenetics and nuclear signaling
Target protein
NPY6R
