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Home > Product > Antibody > Ob Polyclonal Antibody

Ob Polyclonal Antibody

Ob Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC-p, IF, ELISA

Product overview

Full product name

Leptin

Code

BT-AP12166

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human Ob. AA range:36-85

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.

Uniprot accession

Molecular weight

18641

Gene ID

Human: 3952; Mouse: 16846; Rat: 25608

Synonyms

Leptin; LEP; OB; OBS; Leptin; Obese protein; Obesity factor

Research area

Cardiovascular; Metabolism; Neuroscience; Signal transduction; Stem cells

Target protein

LEP

Recommended dilution

Application Dilution
IHC-p 1: 100 - 1: 300
ELISA 1: 10000

Images

Immunohistochemistry analysis of Ob antibody in paraffin-embedded human breast carcinoma tissue.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

Add to Cart

Lead time: Within one week

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