Pancreatic prohormone

BT-AP12735

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 10-90

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Human:;Mouse:;Rat:;

Human: 5539

Pancreatic prohormone ;Pancreatic polypeptide;PP;Obinepitide [Cleaved into: Pancreatic hormone ;PH; Pancreatic icosapeptide ;PI]

Signal transduction

PPY