Full product name
Partitioning defective 6 homolog gamma
Code
BT-AP12784
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 240-320
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
The pseudo-CRIB domain together with the PDZ domain is required for the interaction with Rho small GTPases.,Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.,Belongs to the PAR6 family.,Contains 1 OPR domain.,Contains 1 PDZ (DHR) domain.,Contains 1 pseudo-CRIB domain.,subunit:Interacts with PARD3 (Probable). Interacts with GTP-bound forms of CDC42, ARHQ/TC10 and RAC1. Interacts with the N-terminal part of PRKCI and PRKCZ.,tissue specificity:Widely expressed, with a higher expression in fetal and adult kidney.,
Uniprot accession
Gene ID
Human: 84552
Synonyms
Partitioning defective 6 homolog gamma ;PAR-6 gamma;PAR6D
Research area
Cell biology; Signal transduction
Target protein
PARD6G