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Home > Product > Antibody > PARP-1 Polyclonal Antibody

PARP-1 Polyclonal Antibody

PARP-1 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

Product overview

Full product name

Poly [ADP-ribose] polymerase 1

Code

BT-AP12793

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from the Internal region of human PARP-1.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Uniprot accession

Molecular weight

113084

Gene ID

Human: 142; Rat: 25591

Synonyms

Poly [ADP-ribose] polymerase 1; PARP1; ADPRT; PPOL; Poly [ADP-ribose; polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD;+ ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose; synthase 1

Research area

Epigenetics and nuclear signaling; Signal transduction

Target protein

PARP1

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
ELISA 1: 10000

Images

Western blot analysis of RAT-MUSLE using PARP1 antibody. Antibody was diluted at 1:1000. Secondary antibody was diluted at 1:20000

Protocols

Customer reviews and Q&As

No reviews
No reviews

Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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