Full product name
Serine/threonine-protein kinase N3
Code
BT-AP13131
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,The C1 domain does not bind the diacylglycerol (DAG).,enzyme regulation:Two specific sites, Thr-718 (activation loop of the kinase domain) and Thr-860 (turn motif), need to be phosphorylated for its full activation.,Contributes to invasiveness in malignant prostate cancer.,PTM:Autophosphorylated.,Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.,Contains 1 AGC-kinase C-terminal domain.,Contains 1 protein kinase domain.,Contains 3 REM (Hr1) repeats.,subcellular location:Nuclear and perinuclear Golgi region.,tissue specificity:Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.,
Uniprot accession
Gene ID
Human: 29941
Synonyms
Serine/threonine-protein kinase N3 ;EC 2.7.11.13;Protein kinase PKN-beta;Protein-kinase C-related kinase 3
Research area
Signal transduction
Target protein
PKN3
