Full product name
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
Code
BT-AP13302
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 340-420
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.
Uniprot accession
Gene ID
Human: 57580
Synonyms
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein ;P-Rex1;PtdIns;3,4,5-dependent Rac exchanger 1
Research area
Cell biology; Signal transduction
Target protein
PREX1
