Full product name
Sodium/nucleoside cotransporter 1
Code
BT-AP14009
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
Sodium-dependent and pyrimidine-selective. Exhibits the transport characteristics of the nucleoside transport system cit or N2 subtype (N2/cit) (selective for pyrimidine nucleosides and adenosine). It also transports the antiviral pyrimidine nucleoside analogs 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxycytidine (ddC). It may be involved in the intestinal absorption and renal handling of pyrimidine nucleoside analogs used to treat acquired immunodeficiency syndrome (AIDS). It has the following selective inhibition: adenosine, thymidine, cytidine, uridine >> guanosine, inosine.,polymorphism:Three variant forms of isoform 1 (A, B and C) are expressed in the kidney. All three variant forms have similar nucleoside transport activity.,Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.,tissue specificity:Expressed in kidney.,
Uniprot accession
Gene ID
Human: 9154
Synonyms
Sodium/nucleoside cotransporter 1 ;Concentrative nucleoside transporter 1;CNT 1;hCNT1;Na;+/nucleoside cotransporter 1;Sodium-coupled nucleoside transporter 1;Solute carrier family 28 member
Research area
Signal transduction
Target protein
SLC28A1
