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Home > Product > Antibody > SCNBA Polyclonal Antibody

SCNBA Polyclonal Antibody

SCNBA Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Rat, Mouse

Applications: WB, ELISA

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB, ELISA

Product overview

Full product name

Sodium channel protein type 11 subunit alpha

Code

BT-AP14080

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from part region of human protein

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.

Uniprot accession

Gene ID

Human: 11280

Synonyms

Sodium channel protein type 11 subunit alpha ;Peripheral nerve sodium channel 5;PN5;Sensory neuron sodium channel 2;Sodium channel protein type XI subunit alpha;Voltage-gated sodium channel su

Research area

Neuroscience

Target protein

SCN11A

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
ELISA 1: 5000 - 1: 20000

Protocols

Customer reviews and Q&As

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Product size

Price

  • 100ul

    $275.00

  • 50ul

    $180.00

  • 20ul

    $108.00

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Lead time: Within one week

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