Full product name
Serine/threonine-protein kinase Sgk1
Code
BT-AP14164
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human SGK around the phosphorylation site of Ser78. AA range:41-90
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Uniprot accession
Molecular weight
48942
Gene ID
Human: 6446; Mouse: 20393
Synonyms
Serine/threonine-protein kinase Sgk1; SGK1; SGK; Serine/threonine-protein kinase Sgk1; Serum/glucocorticoid-regulated kinase 1
Research area
Developmental biology; Signal transduction; Stem cells
Target protein
SGK1