Full product name
Actin alpha skeletal muscle
Code
BT-AP15725
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthetic Peptide of α-Skeletal Muscle Actin
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Storage
-20°C for 1 year
Background
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
Uniprot accession
Molecular weight
42051
Gene ID
Human: 58; Mouse: 11459; Rat: 29437
Synonyms
Actin alpha skeletal muscle; ACTA1; ACTA; Actin, alpha skeletal muscle; Alpha-actin-1
Research area
Cardiovascular; Signal transduction; Stem cells
Target protein
ACTA1
