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Product > Antibody > ILK Monoclonal Antibody
ILK Monoclonal Antibody
ILK Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 3A9
Host: Mouse
Reactivity:Human, Mouse, Monkey
Applications: WB,IHC,FCM
Product Summary
Size:
50μL
Clonality: 3A9
Host: Mouse
Reactivity: Human,Mouse,Monkey
Applications: WB,IHC,FCM
Product overview
Code
BT-MCA4526
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
3A9
Immunogen
Purified recombinant fragment of human ILK (AA: 97-244) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
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