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Product > Antibody > CEBPA Monoclonal Antibody
CEBPA Monoclonal Antibody
CEBPA Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 4E10
Host: Mouse
Reactivity:Human
Applications: WB,FCM
Product Summary
Size:
50μL
Clonality: 4E10
Host: Mouse
Reactivity: Human
Applications: WB,FCM
Product overview
Code
BT-MCA3321
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
4E10
Immunogen
Purified recombinant fragment of human CEBPA expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
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