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Product > Antibody > HSP90AA1 Monoclonal Antibody
HSP90AA1 Monoclonal Antibody
HSP90AA1 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 5G5
Host: Mouse
Reactivity:Human, Mouse, Monkey
Applications: WB,IHC,FCM
Product Summary
Size:
50μL
Clonality: 5G5
Host: Mouse
Reactivity: Human,Mouse,Monkey
Applications: WB,IHC,FCM
Product overview
Code
BT-MCA4180
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
5G5
Immunogen
Purified recombinant fragment of human HSP90AA1 expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1, an inducible form, and HSP90AB1 (MIM 140572), a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).
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