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Product > Antibody > GPC3 Monoclonal Antibody
GPC3 Monoclonal Antibody
GPC3 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 9C2
Host: Mouse
Reactivity:Human, Mouse, Rat
Applications: WB,IHC,ICC,FCM
Product Summary
Size:
50μL
Clonality: 9C2
Host: Mouse
Reactivity: Human,Mouse,Rat
Applications: WB,IHC,ICC,FCM
Product overview
Code
BT-MCA3128
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
9C2
Immunogen
Purified recombinant fragment of human GPC3 expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
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