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Home > Product > Antibody > GRIA2 Monoclonal Antibody

GRIA2 Monoclonal Antibody

GRIA2 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB,FCM

Product overview

Code

BT-MCA2305

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human GRIA2 (AA: 652-807) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene.

Uniprot accession

Molecular weight

98.8kDa

Gene ID

2891

Synonyms

GluA2;GluR2;gluR-B;GluR-K2

Research area

Neuroscience

Target protein

GRIA2

Recommended dilution

Application Dilution
WB 1:500 - 1:2000
FCM 1:200 - 1:400
ELISA 1:10000

Images

Western blot analysis using GRIA2 mAb against human GRIA2 recombinant protein. (Expected MW is 43 kDa)
Western blot analysis using GRIA2 mAb against HEK293 (1) and GRIA2 (AA: 652-807)-hIgGFc transfected HEK293 (2) cell lysate.
Western blot analysis using GRIA2 mouse mAb against HeLa (1) cell lysate.
Flow cytometric analysis of SK-N-SH cells using GRIA2 mouse mAb (green) and negative control (red).
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Protocols

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Product size

Price

  • 100μL

    $320.00

  • 50μL

    $220.00

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Lead time: Within one week

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