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Product > Antibody > GRIA2 Monoclonal Antibody
GRIA2 Monoclonal Antibody
GRIA2 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 7G6
Host: Mouse
Reactivity:Human
Applications: WB,FCM
Product Summary
Size:
50μL
Clonality: 7G6
Host: Mouse
Reactivity: Human
Applications: WB,FCM
Product overview
Code
BT-MCA2305
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
7G6
Immunogen
Purified recombinant fragment of human GRIA2 (AA: 652-807) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene.
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