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Product > Antibody > PPP1CA Monoclonal Antibody
PPP1CA Monoclonal Antibody
PPP1CA Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 5E9
Host: Mouse
Reactivity:Human
Applications: WB
Product Summary
Size:
50μL
Clonality: 5E9
Host: Mouse
Reactivity: Human
Applications: WB
Product overview
Code
BT-MCA4534
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
5E9
Immunogen
Purified recombinant fragment of human PPP1CA expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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