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Home >
Product > Antibody > NEFL Monoclonal Antibody
NEFL Monoclonal Antibody
NEFL Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 2G10
Host: Mouse
Reactivity:Human
Applications: WB,IHC,ICC,FCM
Product Summary
Size:
50μL
Clonality: 2G10
Host: Mouse
Reactivity: Human
Applications: WB,IHC,ICC,FCM
Product overview
Code
BT-MCA3752
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
2G10
Immunogen
Purified recombinant fragment of human NEFL expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
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