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Product > Antibody > NEDD8 Monoclonal Antibody
NEDD8 Monoclonal Antibody
NEDD8 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 5B8
Host: Mouse
Reactivity:Human
Applications: WB,IHC,ICC,FCM
Product Summary
Size:
50μL
Clonality: 5B8
Host: Mouse
Reactivity: Human
Applications: WB,IHC,ICC,FCM
Product overview
Code
BT-MCA2330
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
5B8
Immunogen
Purified recombinant fragment of human NEDD8 expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.Tissue specificity: Highly expressed in heart, skeletal muscle, spleen, thymus, prostate, testis, ovary, colon and leukocytes.
We are continuously updating our Antibody catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.
