We use cookies to give you the best experience. By using bt-laboratory.com, you
consent to our use of cookies. If you do not wish to receive our cookies, adjust your browser settings. Read
our Cookies
Policy to learn more.
Reject All
Accept All Cookies
We use cookies to give you the best experience. By using bt-laboratory.com,
you consent to our use of cookies. If you do not wish to receive our cookies, adjust your browser settings.
Read our Cookies
Policy to learn more.
Home >
Product > Antibody > UBB Monoclonal Antibody
UBB Monoclonal Antibody
UBB Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 3C12
Host: Mouse
Reactivity:Human
Applications: WB,FCM
Product Summary
Size:
50μL
Clonality: 3C12
Host: Mouse
Reactivity: Human
Applications: WB,FCM
Product overview
Code
BT-MCA2743
Host
Mouse
Isotype
Mouse IgG1
Size
50μL
Clonality
3C12
Immunogen
Purified recombinant fragment of human UBB expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.
We are continuously updating our Antibody catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.