RPS6KB1 Monoclonal Antibody

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Home > Product > Antibody > RPS6KB1 Monoclonal Antibody

RPS6KB1 Monoclonal Antibody

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: IHC,FCM

Product Summary

Size: 100μL,50μL

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: IHC,FCM

Product overview

Code

BT-MCA3615

Host

Mouse

Isotype

Mouse IgG1

Size

100μL,50μL

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of human RPS6KB1 expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

Store at 4°C short term. Aliquot and store at -20°C long term.

Background

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.

Uniprot accession

P23443:;

Molecular weight

59kDa

Gene ID

6198

Synonyms

S6K;PS6K;S6K1;STK14A;p70-S6K;p70-alpha;p70(S6K)-alpha

Research area

Cell Biology

Target protein

RPS6KB1

Recommended dilution

Application	Dilution
WB	1:500 - 1:2000
IHC-p	1:200 - 1:1000
FCM	1:200 - 1:400
ELISA	1:10000

Images

Western blot analysis using RPS6KB1 mAb against human RPS6KB1 (AA: 295-524) recombinant protein. (Expected MW is 59 kDa)

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using RPS6KB1 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded muscle tissues using RPS6KB1 mouse mAb with DAB staining.

Flow cytometric analysis of Jurkat cells using RPS6KB1 mouse mAb (green) and negative control (red).

Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

100μL

$320.00
50μL

$220.00

Add to Cart

Lead time: Within one week

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