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Home >
Product > Antibody > MMP9 Monoclonal Antibody
MMP9 Monoclonal Antibody
MMP9 Monoclonal Antibody
Product Summary
Size:
50μL
Clonality: 5C3
Host: Mouse
Reactivity:Human
Applications: FCM
Product Summary
Size:
50μL
Clonality: 5C3
Host: Mouse
Reactivity: Human
Applications: FCM
Product overview
Code
BT-MCA4714
Host
Mouse
Isotype
Mouse IgG2a
Size
50μL
Clonality
5C3
Immunogen
Purified recombinant fragment of human MMP9 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
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